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KMID : 1159320220240040445
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Korean Journal of Vision Science
2022 Volume.24 No. 4 p.445 ~ p.452
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Preparation of Blue-Light Blocking Hydrogel Contact Lenses Using Reactive Orange 16 Dye
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Kim Jong-Lae
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Abstract
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Purpose : Blue-light blocking dyes were chemically conjugated to the hydrogel contact lenses. Blue-light blocking properties of the resultant contact were investigated, and the amounts of attached dyes were quantified.
Methods : Vinyl sulfone-based Reactive Orange 16 Dyes were covalently conjugated to hydrogel contact lenses containing a considerable amount of alcohol groups. The investigation for blue-light blocking properties of the hydrogel lenses and the quantification for the amounts of attached dyes were performed using UV-vis spectrophotometer.
Results : The blue-light blocking Reactive Orange 16 Dyes were successfully conjugated to the hydrogel contact lenses. The resultant contact lenses exhibited good blue-light blocking properties according to the results of the UV-vis spectra investigation. Reactive Orange 16 Dye conjugated to contact lenses was quantified using Beer-Lambert's law, and the blue-light blocking rate of contact lenses could be controlled by adjusting the concentration of reactive dye.
Conclusion : In this study, a reactive dye with a blue-light blocking function was fixed to hydrogel contact lenses through chemical bonding, and their blue-light blocking function was analyzed. It was confirmed that as the concentration of the blue-light blocking dye increased in the chemical reaction, the blocking intensity in the blue light wavelength region between 380 and 500 nm and the amount of the conjugated dye also increased. The development of blue-light blocking contact lenses that can be mass-produced is expected to play an important role in the development of functional ophthalmic optical medical devices.
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KEYWORD
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Blue-light, Contact Lens, Hydrogel, Reactive dyes
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